The Big Experiment
Ever wondered how technology start-ups, well, start-up? For most founder entrepreneurs, it is the biggest experiment they'll ever run. Like most experiments, the result isn't known beforehand and it often doesn't work first time. On a bigger scale, how do big tech companies turn innovative science into profit?
Mark Davison interviews founder scientists, executives, investors, communicators, and others in the technology start-up and corporate science ecosystems.
Learn how great ideas turned into thriving businesses (or not) from those who made it happen (or didn't). Get business tips, lessons learned, and life lessons straight from the people who know.
Inspiring, disastrous, funny: hear what life in a science-driven company is really like.
Straight-talking, no nonsense, but conversational style. All technical content is explained for the non-specialist - you don't need a PhD or fluency in jargon and technobabble.
The Big Experiment
James Dooley: Transforming clinical treatment of neuroinflammatory conditions
Imagine being able to internalise the pharmaceutical factory into the human.
You could avoid the contamination risks and need for purification in biologic production.
In this episode I am joined by Dr James Dooley who is doing just this with his work at Aila Biotech. James and his team developed technology to drive the production of immune-regulating biologics at the exact site of disease. Through precise spatial and temporal control over biologic expression, Aila Biotech can prevent neuroinflammatory damage in brain injury.
James discusses his journey into science and how this work began. As well as the challenges that come with having to focus on the business, not just the science. He also reflects on what he might do differently if he were to start again.
“We really think we can have a dramatic effect on people's quality of life long term” – James Dooley
You’ll hear about:
01:50 – James’ journey into science
06:52 – James on drug delivery by adeno associated viruses
13:26 - What's the specificity of infection?
19:38 - Is there an invisible downside?
23:32 – James on the challenges of focusing on the business
28:47 – Will James be taking the therapy into the clinic?
36:25 – Would James do anything differently next time?
Follow James:
LinkedIn - https://www.linkedin.com/in/james-dooley-96b4a62a/
Aila Biotech - https://www.ailabiotech.com/
Connect with Me:
LinkedIn: https://www.linkedin.com/in/markdavison100/
Grant Instruments: https://www.grantinstruments.com/
Grant Instruments on LinkedIn: https://www.linkedin.com/company/grant-instruments-cambridge-ltd/
